Super Knock-in Cocktail

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Substance mix that transiently maximizes HDR efficiency and prevents off-target editing.

The Super Knock-in Cocktail is a specialized formulation designed to transiently enhance HDR efficiency during genome editing up to 93%. This mix significantly boosts the precise insertion of desired genetic sequences while minimizing unwanted off-target edits. This results in improved editing accuracy, higher success rates, and safer outcomes for genome editing experiments across diverse biotech applications.

Key features

Higher proportion of precise edits

Promotes a precise repair pathway, increasing the proportion of cells carrying the intended genomic modification.

Prevents off-target effects

Drastically reduces off-target editing, reaching 0% even in regions prone to off-target events.

Increased knock-in efficiency

Achieves a 5.4-fold median increase in precise knock-in efficiency compared to standard editing across 30 targets.

Simple workflow integration

Integrated by directly adding to CRISPR reagents and cell culture media, with no additional handling steps or protocol changes required.

This kit is available for testing

Try our solutions in your lab and assess their impact on your editing outcomes. Early testers get hands-on access before launch and direct support from our team.